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For weight management, patients not meeting criteria for GLP-1 medications might consider other licensed options such as orlistat, which is available over-the-counter at lower cost, though with more modest efficacy

Deviating too far from this ratio can result in an unnatural appearance, especially if the upper lip is much larger than the lower

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Effect of side-chain shortening on the physiologic properties of bile acids: hepatic transport and effect on biliary secretion of 23-nor-ursodeoxycholate in rodents