422 Additional therapeutic candidates have encountered unique translational challenges
Most importantly, neither agent has raised major red flags in terms of serious adverse events in the trials conducted to date
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HFFs (AG14608) were obtained from the NIA Repository, administered by the Coriell Institute for Medical Research, Camden, New Jersey
In most cases, drug-induced hair graying is reversible by reducing the dose or discontinuing the offending medication
With a combination protocol that may produce more rapid weight loss than monotherapy, the risk is theoretically higher