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doi: 10.1038/npp.2009.104 162 PytkaK.DziubinaA.MlyniecK.DziedziczakA.ZmudzkaE.FurgalaA.et al

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But when it is taken with other diabetes medicines like insulin or sulfonylureas, it can lead to dangerously low blood sugar levels

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Thiazolidinediones (pioglitazone): Often cause significant weight gain plus fluid retention