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some agents have shown reduction in major adverse cardiovascular events in specific populations [28] [29] Renal protection : slowing of diabetic kidney disease progression across the class Weight loss : modest reduction in body weight Blood pressure reduction : mild antihypertensive effect SGLT2 inhibitors do carry risks including genital mycotic infections and, rarely, euglycaemic diabetic ketoacidosis

For review articles in particular, explicit articulation of decision criteria strengthens credibility by demonstrating that inclusion reflects systematic reasoning rather than narrative convenience

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European public assessment reports

DISCUSSION This study indicated that after 12 weeks of treatment, 90.32% of patients in the semaglutide-intensified treatment group experienced a weight reduction

endotoxin (LAL) per USP