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In their separate Phase 2 trials, retatrutide monotherapy showed larger weight loss (~24.2% at 48 weeks, 12 mg) than standalone cagrilintide (~10.8% at 26 weeks, 4.5 mg), and indirect network meta-analyses rank retatrutide highly

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Tirzepatide Weight Loss Results In the landmark SURMOUNT-1 trial published in the New England Journal of Medicine , participants receiving the highest dose of tirzepatide (15 mg weekly) achieved an average reduction of approximately 20.9% of body weight over 72 weeks

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Contributed reagents/materials/analysis tools: H