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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 18 Relative Effectiveness and Safety of the GLP-1 (Glucagon-Like Peptide 1) Receptor Agonists, Semaglutide and Liraglutide in the Treatment of Obese Type 2 Diabetics: A Prospective Observational Cohort Study in Poland Authors Hoffmann K, Michalak M , Paczkowska A Received 1 April 2025 Accepted for publication 1 July 2025 Published 7 August 2025 Volume 2025:18 Pages 27232738 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Halis Akturk Karolina Hoffmann, 1 Micha Michalak, 2 Anna Paczkowska 3 1 Department and Clinic of Internal Diseases and Metabolic Disorders, Poznan University of Medical Sciences, Pozna, Poland

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GLP-1 medications carry risks including pancreatitis, gallbladder disease, and potential thyroid C-cell tumours based on animal studies
Similarly, the trend remained unchanged in the stratified analysis according to the status of comorbidities, including MASH, LC, heart failure, T2D and CKD
It increases thermogenesis