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Purified recombinant protein was prepared as previously described 49, 55 and diluted in reaction buffer to a concentration of 1.25 M, so that in the plate assay, the final concentration is 1 M

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Unlike CJC-1295 with DAC, the no-DAC variant does not include the Drug Affinity Complex for albumin binding, resulting in a shorter half-life of approximately 30 minutes and a more physiologically pulsatile GH release profile in research models

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