In parallel, glycine, another major component of collagen, is synthesized from serine, which is derived from the glycolytic intermediate 3-phosphoglycerate via the enzymes phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine phosphatase (PSPH), and subsequently converted by serine hydroxymethyltransferase 1/2 (SHMT1/2) [17, 18]
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Tu et al., 2014)
This neovascularization phenomenon was consistently observed in murine full-thickness burn injuries (Fig
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