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J Womens Health (Larchmt)

SGLT2 inhibitors and GLP-1s have trial-level evidence showing they slow kidney disease, reduce cardiovascular events, and extend life

Supplements that can increase GLP-1 levels include psyllium, berberine, yerba mate, curcumin, ginseng, and wild bitter gourd

Assessment and monitoring: Be vigilant for signs that your diabetes management may be affected, including: Elevated blood glucose readings above your usual range Increased thirst or urination (signs of hyperglycaemia) Unusual fatigue or lack of energy Return of symptoms that were previously well-controlled If you experience severe symptoms such as persistent vomiting, severe abdominal pain, or signs of pancreatitis (rare but serious), seek urgent medical attention from your GP, NHS 111, or 999 as appropriate

doi:10.1002/ajmg.b.32272

According to clinical trials, people who take semaglutide lose an average of 15% of their body weight over a year