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It is therefore apparent that most studies in this area have been limited by small sample size (and therefore reduced power) and that most have focused on the acute effect of metformin therapy as opposed to its longer term effects

Lancet 346 : 13951398

Redox regulation of pancreatic cancer cell growth: role of glutathione peroxidase in the suppression of the malignant phenotype

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Consulting with a healthcare provider or dermatologist can help determine the best course of action