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A broad spectrum of antidepressant drugs, such as selective serotonin reuptake inhibitors (SSRI), tricyclic antidepressants, selective dopamine reuptake inhibitors, and selective norepinephrine reuptake inhibitors (SNRI), is introduced to change serotonergic, dopaminergic, glutamatergic, or noradrenergic activity levels in the central nervous system (CNS) (Harmer, Duman, and Cowen, 2017)

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One important cytokine-regulated signaling cascade that is essential for triggering innate immunity, coordinating adaptive immune processes, and eventually reducing inflammation and immunological responses is the JAK/STAT pathway (112)

doi:10.1089/rej.2001.4.133 2

By the end of the week, many people feel comfortable enough to return to daily activities and work