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Treating ischemically damaged porcine kidneys with human bone marrow- and adipose tissue-derived mesenchymal stromal cells during ex vivo normothermic machine perfusion

Ferroptosis, an iron-dependent form of programmed cell death first identified by Dixon et al., is characterized by excessive intracellular iron accumulation, lipid peroxidation and distinct biochemical and morphological features (Liu et al., 2021)

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With chronic disease, there is an increase in inflammation and oxidative stress leading to an increased need for glutathione