enteric-coated versions offer some protection from gastric degradation Liquid / sublingual drops faster mucosal contact
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However, evidence of the beneficial effects of treating patients with hyperprolactinemia to obtain improved metabolic status is lacking
In contrast, a double-blinded, placebo-controlled trial on the daily supplementation of selenium in hyperthyroid patients with Graves disease showed no positive effects on recurrence rate [31]
The latter is also supported by the TODINELI-trial (Brock et al., 2019), where treatment of type 1 diabetic patients with liraglutide reduced levels of proinflammatory cytokines (IL-6) but did not improve the status of patients that had already established autonomic or diabetic polyneuropathy
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