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Mean body-weight reduction as a weekly GLP-1 agonist2.4 mg 68 wk Wilding, NEJM 2021

SURMOUNT-5 is a Phase 3b randomized clinical trial that directly compared tirzepatide (Zepbound) to semaglutide (Wegovy) for weight loss in 751 adults with obesity over 72 weeks

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Studies suggest that diets rich in soluble fiber can improve satiety, support healthy blood sugar levels, and reduce overall calorie intake, making fiber-rich foods an important part of natural GLP-1 support and sustainable weight management

If Im already sensitive to caffeine, I treat that as a yellow flag and adjust my routine (like not stacking it with coffee)