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Hypercobalaminemia: Definition Hypercobalaminemia is the term used to describe an overdose of vitamin B12 (cobalamin)

Specifically, upregulation of ABC transporters, such as ABCB1 (P-glycoprotein), can lead to increased drug efflux, reducing intracellular drug concentration and efficacy (61)

When bone tissue is broken down by osteoclasts (the cells responsible for resorption), collagen fibers are degraded and deoxypyridinoline is released into circulation

Data in panel a,d,e,h,j and l were analyzed using 2-way ANOVA and with Bonferroni post-hoc comparison of individual time points

When exposed to 0.5% and 1% L-carnitine, these cells showed a significant increase in -oxidation , i.e., the process of fatty acid breakdown within the mitochondria

Ruas JS, Siqueira-Santos ES, Amigo I, Rodrigues-Silva E, Kowaltowski AJ, Castilho RF