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According to the Mayo Clinic, women with a BMI over 30 have an increased risk of the following: Miscarriage (which can increase by up to 50% in BMIs over 35) Gestational diabetes Preeclampsia Heart conditions Sleep apnea C-section surgery upon delivery There is no exact number that guarantees infertility or pregnancy problems

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Zhang S, Fu J, Zhang Q, et al

Unfortunately, synthetic folic acid can be highly problematic for individuals with the MTHFR gene variation, as they may have a difficult time processing this form of folate