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This regulation occurs via both SMAD-dependent and non-canonical (PI3K/mTORC2/PDGFR) signaling pathways, and is reinforced by Sirtuin-7 downregulation, which reduces Forkhead box protein O4 (FOXO4)-mediated suppression of GLS1 expression [100]

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Potential for Side Effects : Although glutathione is generally regarded as safe, some individuals may experience side effects or allergic reactions

(2013), Vipera russelli snake venoms induced reactive oxygen species (ROS) when injected into experimental mice with depletion of antioxidant defences like glutathione, superoxide dismutase, and catalase (Santhosh et al

10.1038/s12276-020-0438-5 125 ShuklaS