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There is some evidence that the diabetes drug metformin (Glucophage) may reduce vitamin B12 absorption when used for several years

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While its best-known role is in erythropoiesis (red blood cell formation), its also involved in: DNA synthesis Regeneration of bone marrow, GI lining, and respiratory tract lining Nervous system development and maintenance (11) Prevention of anemia Although a B12 deficiency isnt as common as vitamin D or even folate, it still happens