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J Intern Med (2004) 256(1):114

The available data and in particularly those in human studies show a very low rate of fermentation (if at all) with little SCFA production and thus a very low caloric yield

Even though Egger's test was not statistically significant, publication bias cannot be rolled out since positive studies are more likely to be published than negative ones, particularly if they were sponsored by the medication's manufacturer, which is the case for included studies

Yuen KCJ, Biller BMK, Radovick S, et al

Third-party testing certificates (also called Certificates of Analysis or COAs) should confirm peptide identity and purity, ideally through HPLC and mass spectrometry

This effect is dose-dependent, peaks around week 24, and diminishes thereafter even with continued treatment