MACE: major cardiovascular events
GLP-1 receptor agonists-SGLT-2 inhibitors combination therapy and cardiovascular events after acute myocardial infarction: an observational study in patients with type 2 diabetes
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A systematic review and meta-analysis of randomized controlled trials found that chromium supplementation significantly improved glycemic control in patients with type 2 diabetes
To avoid this pitfall, we here use PAR2-mutant mice (PAR2-G37I and PAR2-R38E) that retain activation-independent signaling receptor platforms involving PAR2, while abolishing cleavage sensitivity to specific proteases (21, 22, 30, 31)
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