Retatrutide is an investigational triple receptor agonist that simultaneously activates glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors
Sci Rep 6 , 29240 (2016)
The peptide activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, promoting cell survival and inhibiting apoptosis in stressed cells
1 Direct receptor effects , more speculative research has explored GLP-1 receptor expression in dermal fibroblasts and adipose-derived stem cells, theorizing that receptor activation could alter local cytokine signaling in the scalp, though this remains an active area of investigation rather than established fact
WARNING : California Proposition 65 WARNING: Consuming this product can expose you to chemicals, including lead, which are known to the State of California to cause birth defects or other reproductive harm
INCI naming and regulatory considerations For EU CPNP notification and most international cosmetic-regulatory frameworks, INCI names must appear in the finished-product ingredient list: GHK-Cu : Copper Tripeptide-1 AHK-Cu : Custom INCI required
