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Please contact us immediately if you experience any of the following: Fever of 100.4F (38C) or higher Blistering at the injection site Muscle aches, nausea, dizziness, or headache (if severe or persistent) Skin rash, severe itching, vomiting, or hives TIPS TO REDUCE SIDE EFFECTS BOOK NOW Start with a Lower Dose: Begin with the lowest recommended dose to allow your body to acclimate and reduce the likelihood of side effects

Common transition side effects When switching from tirzepatide to semaglutide, some side effects may reappear, especially during the start of medication or during dose escalation

Acknowledgements The authors would like to thank the patients who participated, the investigators, all trial site staff and all Novo Nordisk employees involved in these trials

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