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Understanding that GLP-1 medications take time to reach therapeutic levels prevents discouragement during the early titration phase

GLP-1 therapy uses glucagon-like peptide-1based medications to support metabolic regulation

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Trial data can help patients understand general medication trends, but a physician must interpret that information in the context of the individual patients health history, side-effect risk, current medications, and long-term goals

Of these trials, four compared DPP-4 inhibitors against placebo (SAVOR-TIMI 53, EXAMINE, TECOS, CARMELINA), eight compared GLP-1RA against placebo (ELIXA, LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND, PIONEER 6, AMPLITUTE-O) and eleven compared SGLT-2 inhibitors against placebo (EMPA-REG, CANVAS, DECLARE, CREDENCE, DAPA-HF, DAPA CKD, VERTIS-CV, EMPEROR-R, SCORED, SOLOIST-WHF, EMPEROR-P)