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STEP trial participants who reached the 2.4 milligram weekly dose lost an average of 22% of their body weight over 68 weeks, while lower-dose cohorts saw proportionally less dramatic results

Semaglutide is a compounded prescription injection that mimics a natural hormone called GLP-1 (glucagon-like peptide-1)

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10.1073/pnas.2017205118 Summary Keywords membrane contact sites, lipid droplets, mitochondria, endoplasmic reticulum, lysosome, vacuole, cytoskeleton, lipophagy Citation Liao P-C, Yang EJ, Borgman T, Boldogh IR, Sing CN, Swayne TC and Pon LA (2022) Touch and Go: Membrane Contact Sites Between Lipid Droplets and Other Organelles

Semaglutide has a half-life of about 7 days, meaning half the drug is cleared from your body each week

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