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The safety has not been well studied

With heterogeneous evidence of the cardiovascular benefit, mortality, and potential risks of intensive glycemic control reported in several recent clinical trials, achieving good blood glucose control without increasing cardiovascular risk factors such as hypoglycemia and body weight gain is becoming more important [3,4,5,6,7]

Hwang et al., 2023

Direct the water stream against the vial wall rather than directly onto the peptide powder

The manufacturer must show that these differences do not affect the safety, efficacy, or quality of the drug compared to the brand name drug, Mr

Importantly, there is an absence of data demonstrating development of chronic pancreatitis in humans treated with GLP-1RAs to support this connection