Mol Neurobiol 61 , 15071526 (2024)
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Upon exposure of these macrophages to LPS, the enhancement of intracellular supersulfides via treatment with NAC-S2 almost completely suppressed IL-1 production, which suggests that supersulfides establish a negative feedback loop regulating NLRP3 inflammasome-mediated IL-1 production (110)
La technologie liposomale (Liposovit) utilise dans ce produit encapsule le glutathion dans des phospholipides, une stratgie qui protge le compos de la dgradation dans le tractus digestif et facilite son transport au niveau cellulaire
The mechanism was proposed to involve copper-dependent enzymes (notably lysyl oxidase, which catalyzes the cross-linking of collagen and elastin and requires copper as a cofactor), GHK-specific effects on growth factor activity, and downstream gene-expression effects in fibroblasts and other tissue-repair-relevant cell types