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Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.Neurochem Int, 2007;50(7-8):921-31

Keep a backup gel pack in the freezer

To prevent postural symptoms , patients should adopt careful postural changes rising slowly from lying to sitting, pausing briefly, then standing gradually whilst holding onto a stable surface

Your appetite-suppressing effects may weaken within 24 to 48 hours, and you might notice increased hunger or cravings returning

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