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Research demonstrates that daily dosing at 500-1000mg levels produces measurable increases in cellular glutathione concentrations across multiple tissue types [1]

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The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

Nez-Vergara et al

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Fang, L., Hao, Y., Yu, H., Gu, X., Peng, Q., Zhuo, H., Li, Y., Liu, Z., Wang, J., Chen, Y., Zhang, J., Tian, H., Gao, Y., Gao, R., Teng, H., Shan, Z., Zhu, J., Li, Z., Liu, Y., & Wang, P