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The field is shifting on two axes: (1) from single-target GLP-1R agonists toward multi-receptor co-agonists (GLP-1R/GIPR, GLP-1R/GCGR, triple agonists), and (2) from injectable peptides toward oral small molecule agonists

Athletes using GLP-1s will need to closely watch their diet and training to make sure they maintain muscle (perhaps while dealing with the vomiting, nausea, and diarrhea often associated with GLP-1s)

The ideal option for you depends on several factors, such as your health goals and current health status, weight, and medical history