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The most common side effects are mild nausea, decreased appetite, constipation, or bloating usually temporary as your body adjusts

So, regardless of whether you are taking the recommended 2.4 mg daily, or are taking one single higher dose of the vitamin, the oral supplement form is usually going to suffice for most individuals who suffer from a deficiency

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ANZ J Surg 72:226228

2 Though theoretically the use of NAD+ via various routes of administration for various conditions is promising, data is primarily limited to case studies at this time