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It also underscores why replenishing glutathioneeither directly or through precursorsis a primary therapeutic target for neuroinflammation

(Springer International Publishing AG, Cham, Switzerland), 128

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Moreover, with aging, we all lose the ability to produce and maintain optimal levels of Glutathione: in elderly subjects, the decline in Glutathione levels could be due to different factors including a reduced intake of essential nutrients involved in the production of this molecule, decreased activity of enzymes involved in its synthesis, or an increase in aging-related oxidative stress