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Hirschsprung disease must be considered in infants with delayed passage of meconium (more than 48 hours after birth) or other red flags, even in the setting of normal findings on barium enema examination

1998, by Raun et al

Citrus Allergy From Pollen to Clinical Symptoms

The reason lies in how the body interacts with GLP-1 (glucagon-like peptide-1) receptor agonists

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This happens in the mitochondrial matrix