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Dermatol Surg 2020;46(2):220-228

Smoking Nicotine constricts blood vessels, reducing oxygen and nutrient delivery to skin cells

That exceeds the 24.2% Phase 2 figure thanks to the longer treatment window

Researchers also floated broader hormonal and immune effects as possible secondary factors, though they see weight loss as the likelier explanation

This is the single most important practical point in the GLP-1 vs GLP-2 comparison: the two hormones power two completely different categories of medicine