Allopurinol, the first-line ULT, suffers from reduced efficacy in patients with impaired conversion to its active metabolite, oxypurinol (OXY), and carries risks of severe hypersensitivity reactions (Yi et al., 2024)
Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2TAK1-dependent p38 MAPK-AP1 and IKK-IB-NF-B signaling pathways
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
While methylcobalamin participates in the methylating processes including the synthesis of methionine, the adenosylcobalamin cofactor initiates the transformation of a whole series of substrates into their isomers with an unusual structure [4]
Shi, J., Tong, J
The body produces its own glutathione (GSH) but it is depleted by poor diet, pollution, toxins, medications, stress, trauma, aging, infections, and radiation