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Many steroids convert to estrogen through the aromatase enzyme, producing water retention, potential gynecomastia, and a softer appearance that contradicts recomposition goals

Trial data can help patients understand general medication trends, but a physician must interpret that information in the context of the individual patients health history, side-effect risk, current medications, and long-term goals

The connection is thought to be related to the weight loss itself, rather than a direct effect of the medication

However, they often come with higher out-of-pocket costs, mainly if you use out-of-network providers

If redness or itching persists beyond 3-4 days or progressively worsens, contact your healthcare provider for evaluation

Guedes EP, Hohl A, de Melo TG, Lauand F