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Lancet 366 , 10591062 (2005)

This implies that the interaction between the two vitamins is necessary to achieve meaningful photoprotection by dietary means

(Left) In liver cells, GLP-1 can mediate cholesterol efflux by acting directly on LXR, or by inducing an increase in ATP-binding cassette transporter A1 (ABCA1) mRNA through Ca2+/calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/Prolactin regulatory element binding (CaMKK/CaMKIV/PREB), increasing apolipoprotein AI (apo AI) mRNA and promoter expression, and increasing apo AI secretion, thereby mediating intracellular cholesterol efflux

doi: 10.1016/j.socscimed.2004.10.002

As mentioned, the majority of the research on GLP-1s for PCOS has been in folks who have a higher weight, so its not clear how much of the benefits would translate to people with the condition who fall at lower weights, nor is it known whether the latter folks can safely take these drugs

They may not feel confident in current dosing guidelines, in managing side effects, or in identifying which patients will benefit most from GLP-1s compared with other options