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479,480 This activation often involves focal adhesion kinase (FAK), which is a critical mediator in transducing signals from integrins to promote cell cycle progression and proliferation through pathways like Ras-ERK/MAPK

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While the clinical relevance of these findings in a population largely free from kidney disease remains uncertain, the reductions in albuminuria, blood pressure, and the favourable safety profile support further investigation of retatrutides potential kidney-protective effects in high-risk populations

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10.1021/acs.jproteome.7b00802 3 BelzerC.de VosW

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