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Among other things, these mediators influence TRP ion channels, which is important for pain relief (in lipoedema, ~80 % of those affected suffer from pain)

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In terms of frequency, short-term high-frequency administration (e.g., once daily for 3 consecutive days) enables rapid initiation of therapeutic efficacy, whereas long-term administration once weekly or once every 2 weeks is sufficient to maintain stable improvements, which aligns with clinical practice requirements (Klinger et al., 2021)

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Increases mobility for people with peripheral artery disease