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doi: 10.3390/biomedicines6030091

Kornelius et al

Acquisition of stable inducible upregulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells

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PKA then activates hormone-sensitive lipase (HSL), which accelerates the breakdown of triglycerides into glycerol and free fatty acids

Given the high frequency of musculoskeletal problems in individuals with clEDS (Supplementary Table 1), we propose that coordination of care and follow-up for patients with clEDS lie with (pediatric) rheumatology and if available with specialized EhlersDanlos services