concurrently, BNIP3 recruits Parkin to mitochondria to initiate autophagic flux, whereas NIXas a ubiquitination substrate of Parkinundergoes conformational remodeling post-modification to specifically engage adaptor protein NBR1, ultimately enabling targeted autophagic degradation of compromised mitochondria (Wang et al., 2023)
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Digestive System Research Protocols Common rodent GI protocols include the DSS-induced colitis model (closer to ulcerative colitis), the cysteamine-colitis model, ischemia-reperfusion injury, and surgical anastomosis models
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