Those of us in the hypermobility and fibromyalgia space are well aware of the complex mast cell and inflammatory picture in fibromyalgia, and its worth keeping in mind that the anti-inflammatory effects of GLP-1 drugs have been studied in a pretty specific metabolic context, not in the kind of neuroinflammatory picture we see in central sensitisation states
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If you consult the websites of naturopaths and other wellness gurus selling you the latest detox solutions, however, you might become convinced that they know what they are talking about by their use of terms like binders, die-off symptoms, and herxheimer reactions. Where does that lingo come from
And while it can be prescribed off-label for weight loss, Ozempic typically produces less weight loss than Wegovy
However, the insulin-expressing cells arise mainly from extrainsular progenitors rather than the mature exocrine cells[99]
However, these techniques require additional validation and are not yet widely available for routine clinical use (Reid et al., 2013)