discovered that Okra polysaccharides (OP) from Abelmoschus esculentus (L.) Moecnch exhibited significant improvements in depression-like behavior and alterations in the structure and abundance of gut microbiota within a depressed mouse model of CUMS (Yan et al., 2020)
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In recent years, there have been advances in the development of disease-modifying therapies (DMTs) for AD, with the approval by the US Food and Drug Administration (FDA) of the anti-amyloid monoclonal antibodies aducanumab, lecanemab, and donanemab [11, 12]
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After this initial period, patients are usually moved to the 1.5 mg dose, and then if needed, to the 9 mg maintenance dose, as advised by their doctor