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Prolonged treatment of neuroblastoma cell lines with standard chemotherapy agents, etoposide or doxorubicin showed increased levels and synthesis of GSH, increased expression of -glutamyl-cysteinyl ligase, and decreased depletion of GSH [58, 65]

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It plays a major role in the development and progression of many chronic conditions, including heart disease, kidney disease, sleep apnea, and diabetes, all of which can worsen blood pressure control, she says