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Apovian CM, Aronne L, Rubino D, Still C, Wyatt H, Burns C

Medical eligibility is required and individual results may vary

Data on urate-lowering medicine dispensings in Part B includes patients dispensed at least one of benzbromarone, febuxostat, allopurinol or probenecid

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Of interest, our experiments administering G49 to mice lacking hepatocyte FGF21 in which Fgf21 expression was found elevated upon G49 treatment revealed an extra-hepatic contribution to plasma FGF21 by eWAT and iWAT as reported 59