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2.4.6 PI3K/AKT and Sirtuin1 The autophagy-lysosomal pathway is responsible for maintaining the metabolic balance of the ECM by sequestering FN within the cytosol and activating lysosomes for degradation in fibrosis (Guo et al., 2020)

MPs caused more pronounced anxiety-like behaviors compared to NPs after 30 days of exposure, hypothesizing that NPs are more easily absorbed and removed due to their smaller size, resulting in less neurotoxicity than MPs (Chen et al., 2023)

Why is Glutathione Called the 'Master Antioxidant'

Additional tests (If necessary) Skin biopsy : In rare cases, a skin biopsy might be performed to rule out other conditions or to confirm the diagnosis

however, outcomes are not guaranteed.

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