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In the context of liquid biopsy, biomarkers reflecting peripheral iron homeostasissuch as CSF ferritin and the serum sTfR/ferritin ratiohave demonstrated high sensitivity and specificity in distinguishing mild cognitive impairment (MCI) from AD (Du et al., 2024)

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doi: 10.1097/QAD.0000000000002897 80 TeichmanSLNealeALawrenceBGagnonCCastaigneJPFrohmanLA

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Best Practice & Research Clinical Endocrinology & Metabolism