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Usual target dose: 300 mg per day (150 mg twice daily)

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Results Effect of colistin on mitochondrial membrane potential and oxygen consumption rate in freshly isolated mitochondria To assess the mitochondrial toxicity of colistin, freshly isolated mitochondria were incubated for one hour with 1 M colistin, and then the quenching of the Rho123 fluorescent signal was monitored over time

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Sex differences and subclinical retinal injury in pediatric-onset Ms

A total of 60 patients were randomized to receive LC (3 g/day, n = 30) or placebo ( n = 30) for 7 days