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Weighing risks and benefits of liraglutidethe FDAs review of a new antidiabetic therapy
& Scholz, C
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10.1124/dmd.113.052241PubMed Abstract | CrossRef Full Text | Google Scholar 25 ChanT
Their beneficial mechanisms can include the attenuation of neuroinflammation [e.g., valproate via histone deacetylase (HDAC) inhibition in microglia, downregulating interleukin-1 beta (IL-1) and inducible nitric oxide synthase (iNOS)] or the mitigation of glutamatergic excitotoxicity coupled with enhancement of neurotrophic factor expression (e.g., lamotrigine), thereby conferring antidepressant-like potential (Mula and Sander, 2007
The preservative is what inhibits bacterial growth in a vial that will be accessed more than once, which is why it is specified rather than plain sterile water
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