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Ochratoxin-citrinin as nephrotoxins

When the cinchona tree became scarce in the 1880s, people looked for alternatives, and two fever-reducing agents were developed: acetanilide in 1886 and phenacetin in 1887

In female rats, an increase in the number of females with prolonged diestrus and a decrease in the mean number of corpora lutea resulting in a decrease in the mean number of implantation sites and viable embryos was observed at all dose levels

The science underlying peptides, useful guidelines for safe injection technique, and how to include them into an aesthetic practice is discussed in this paper