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Adequate levels of IGF-1 are needed for the maintenance of bone mass, muscle mass, and brain function at later ages

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These include vitamins A, B, C, D and E, and the minerals zinc, magnesium, selenium, iron, and iodine

Adjust dose to maintain IGF-1 within target range Annual: thorough labs plus assessment of continued need for therapy IGF-1 levels above the upper limit of normal warrant dose reduction

This study supports that TPM is an effective treatment for partial epilepsy [21]